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A descent into Hell is triggered when “Ex-Lord” Donald Brocklebank finds that he must leave Longleigh House for London to find a way to pay for the medical treatments for his wife Nancy. Alone, his over-protected, delusional, adult son, James, fancies himself in charge of the manor house with his terminally ill mother, and barricades the two of them into the house for a series of ever more panicked home treatments, mistakenly protecting her from the arrival of Nurse Mary and any outside help.

In Welville, at Battle Creek, eccentric rich Dr. John Harvey Kellogg (a historical figure) runs a stylish health farm for the wealthy, an idea ahead of his time, based on extreme vegetarianism, neither sex, masturbation or even sensual stimulation, but laughing therapy and purging the ‘polluted’ body, mainly by exercises, often in open air, vicious diet, his invention corn flakes, laxatives, anal yogurt cure, enemas and brutal mechanical cleansing. Eleanor Lightbody drags her sickly, incredulous husband Will along to the therapy; the couple is almost immediately separated and getting horny for more available members of the opposite sex. Kellogs stubbornly willful adopted son (among over 30 kids) George is a filthy embarrassment, paid off just to stay away. Charles Ossining panics when arriving in Battle Creek he finds his aunt’s fortune made him partner in the empty shell- health food company Per-fo, not the planned corn-flakes factory; however with a former Welville-employee and George’s name they hope to get rich from their own cornflakes brand. When an electric therapy goes fatally wrong and several other patients die, Will’s incredulous reluctance turns to panic…

In Chicago, the lonely architect Alex Wyler has a troubled relationship with his father Simon Wyler. In 2004, he buys an old glass house in a lake, designed and built by his father, and he finds a message in his mailbox from the former tenant, the also lonely Dr. Kate Forster, asking to deliver her correspondence in an address downtown. Alex meets his brother Henry in Chicago and when they go to the address with Dr. Forster’s correspondence, they find a building of luxury apartments under construction to be delivered eighteen months later. After some messages, Alex and Kate disclose that she is living in 2006 and Alex in 2004, they fall in love for each other and they try to find means to meet each other.

Ted Striker just got dumped by his long-time girlfriend Elaine Dickinson, who works as a stewardess at Trans American Airlines. In his wish to get her back, he follows her aboard the plane, although he has had a deep aversion against anything winged since he lost several men in the war. During flight, he tries to contact her again and again, but as the crew and many passengers get seriously ill due to a bad fish meal, he has no chance to get to her. In fact, Ted Striker seems to be the only healthy person aboard that has piloting experience. Now, it is up to him to get the bird down in Chicago safely, before the poisoning starts causing casualties. But Ted Striker’s aversion really is a serious psychosis, which breaks open and needs to be cured - right now.

Admitted to Mt. Abaddon Hospital for a routine procedure, George Grieves discovers that his condition is much more serious and complicated than originally expected; and as his own fears begin to manifest around him, he learns that Mt. Abaddon is not a place where people come to get better… it is a place where people come to die.

Malcom Crowe is a child psychologist who receives an award on the same night that he is visited by a very unhappy ex-patient. After this encounter, Crowe takes on the task of curing a young boy with the same ills as the ex-patient. This boy “sees dead people”. Crowe spends a lot of time with the boy (Cole) much to the dismay of his wife. Cole’s mom is at her wit’s end with what to do about her son’s increasing problems. Crowe is the boy’s only hope.