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Miles Raymond, a failed writer and divorcé who teaches junior high school English takes his best friend, former hot actor Jack, on a weeklong drive up to California’s wine country. There they explore the nature of their failures and question their relationships. Jack, about to get married, has an affair with a woman and wonders whether he should call off his wedding. Miles questions whether or not he made the right choice while trying to form a relationship with the woman’s best friend, a fellow oenophile who is a waitress at a restaurant that he frequents often when visiting that part of the country.

A lab accident gives a hound named Shoeshine some serious superpowers — a secret that the dog eventually shares with the young boy who becomes his owner and friend.

The patriarch (Jeff Daniels) of an eccentric Brooklyn family claims to once have been a great novelist, but he has settled into a teaching job. When his wife (Laura Linney) discovers a writing talent of her own, jealousy divides the family, leaving two teenage sons to forge new relationships with their parents. Linney’s character begins dating her younger son’s tennis coach. Meanwhile, Daniels’ character has an affair with the student his older son is pursuing.

A sharp-witted suburban wife, Terry Wolfmeyer, is left to raise her four headstrong daughters when her husband unexpectedly disappears. Things get even more hectic when she falls for her neighbor Denny, a once-great baseball star turned radio d.j. This leaves her daughters out on a limb. They are forced to juggle their mom’s romantic dilemmas as well as their own.

It all begins in a small Oregon town, when shy Sam (RORY CULKIN) confesses to his protective older brother Rocky that he is getting pummeled daily by the towering school bully, George. Together, they plan the perfect payback, inviting George on a birthday river trip tailor-made to end in the bully’s humiliation. Rocky’s pals Clyde and Marty and Sam’s budding girlfriend Millie also join the journey, which starts almost immediately with misgivings. Seeing George in a new light, as a lonely kid desperate for friendship and attention, Sam wants to call the whole thing off. But the boat and the plot are already in motion, and no one can foresee the surprises and accidents that are to come.