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A group of friends whose leisurely Mexican holiday takes a turn for the worse when they, along with a fellow tourist embark on a remote archaeological dig in the jungle, where something evil lives among the ruins.

An aging antique dealer, Jesus Gris, happens upon an elegant mechanized scarab. When opened, it painfully stabs whomever is holding it, but the wound brings youthful vigor and a vampire’s need for blood. The device is relentlessly pursued by a dying tycoon, Dieter de la Guardia, whose nephew Angel, reluctant to see his uncle live a moment longer, must still do the old man’s bidding. Meanwhile, Gris’s desires endanger his own granddaughter, Aurora.

A priest from the Vatican is sent in to investigate claims that a small town in Brazil has a church where statues bleed from the eyes. Meanwhile, a young woman in the U.S. begins to show signs of stigmata, the wounds of Christ. The priest from the Vatican links up with her and cares for her as she is increasingly afflicted by the stigmata. Her ranting and raving finally begins to make sense to the priest who starts to question what his religion has stood for for the last 1900 years.